MAP4K3

Across TCGA patient cohorts, MAP4K3 protein abundance is significantly associated with the RNA expression of many other genes, with 11,253 significant associations in total. GBM shows the largest number of these associations.

The most reproducible MAP4K3-associated genes across cancer lineages are MAP4K3-DT, TNFSF14, and IL2RG. Each is linked with MAP4K3 in more than 5 cancer types. Because this analysis shows association rather than direction, both MAP4K3-to-partner and partner-to-MAP4K3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MAP4K3 versus MAP4K3-DT in OV, with a Pearson correlation of 0.60.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MAP4K3→partner) and Y-score (partner→MAP4K3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	MAP4K3-DT →	+0.563	+0.509	<.001	<.001	3	6
GBM	TNFSF14 →	-0.814	-0.217	<.001	<.001	3	4
HNSC	IL2RG →	-1.015	-0.365	<.001	<.001	3	4
BRCA	LAG3 →	-0.935	-0.177	<.001	.003	3	4
UCEC	TRAJ10 →	-1.253	-0.144	.006	.008	3	4
LSCC	EXOC6B →	+0.522	+0.169	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,253 associations by consensus.

MAP4K3 vs MAP4K3-DT — OV

Explore this scatter interactively →