MAP4K3-DT

Across TCGA patient cohorts, MAP4K3-DT RNA expression is significantly associated with the protein abundance of many other proteins, with 17,917 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible MAP4K3-DT-associated proteins across cancer lineages are MAP4K3, PDZD11, and SPTBN1. Each is linked with MAP4K3-DT in more than 5 cancer types. Because this analysis shows association rather than direction, both MAP4K3-DT-to-partner and partner-to-MAP4K3-DT results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MAP4K3-DT versus MAP4K3 in OV, with a Pearson correlation of 0.60.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MAP4K3-DT→partner) and Y-score (partner→MAP4K3-DT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	MAP4K3 →	+0.509	+0.563	<.001	<.001	3	6
LSCC	PDZD11 →	+0.254	+0.390	<.001	<.001	3	5
GBM	SPTBN1 →	+0.308	+0.285	.001	.001	3	5
BRCA	DDAH1 →	+0.624	+0.324	<.001	.001	3	5
BRCA	ICAM1 →	-0.814	-0.444	<.001	<.001	3	5
GBM	EVI2B →	-0.750	-0.453	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,917 associations by consensus.

MAP4K3-DT vs MAP4K3 — OV

Explore this scatter interactively →