MAP3K4

Across TCGA patient cohorts, MAP3K4 protein abundance is significantly associated with the RNA expression of many other genes, with 6,887 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible MAP3K4-associated genes across cancer lineages are MRPL18, HBS1L, and PCMT1. Each is linked with MAP3K4 in more than 7 cancer types. Because this analysis shows association rather than direction, both MAP3K4-to-partner and partner-to-MAP3K4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MAP3K4 versus MRPL18 in COAD, with a Pearson correlation of 0.47.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MAP3K4→partner) and Y-score (partner→MAP3K4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	MRPL18 →	+0.592	+0.380	<.001	.002	3	8
OV	HBS1L →	+0.629	+0.315	<.001	<.001	3	7
OV	PCMT1 →	+0.645	+0.297	<.001	<.001	3	7
HNSC	TCP1 →	+0.630	+0.345	<.001	<.001	3	7
OV	PDCD2 →	+0.588	+0.384	<.001	<.001	3	7
BRCA	LTV1 →	+0.594	+0.266	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,887 associations by consensus.

MAP3K4 vs MRPL18 — COAD

Explore this scatter interactively →