MAP3K4

Across TCGA patient cohorts, MAP3K4 protein abundance is significantly associated with the protein abundance of many other proteins, with 15,211 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible MAP3K4-associated proteins across cancer lineages are IGF2R, TST, and VTA1. Each is linked with MAP3K4 in more than 6 cancer types. Because this analysis shows association rather than direction, both MAP3K4-to-partner and partner-to-MAP3K4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MAP3K4 versus IGF2R in OV, with a Pearson correlation of 0.43.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MAP3K4→partner) and Y-score (partner→MAP3K4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	IGF2R →	+0.371	+0.329	<.001	<.001	3	6
PDAC	TST →	-0.626	-0.299	<.001	<.001	3	6
OV	VTA1 →	+0.355	+0.282	.005	.005	2	7
HNSC	MAP3K4_S1252 →	+0.730	+0.372	<.001	<.001	3	6
PDAC	MAP3K4_S214 →	+0.755	+0.384	<.001	<.001	3	6
HNSC	MAP3K4_S431 →	+0.619	+0.444	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,211 associations by consensus.

MAP3K4 vs IGF2R — OV

Explore this scatter interactively →