MAP3K4

Across TCGA cell cohorts, MAP3K4 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,879 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MAP3K4-associated GO terms across cancer lineages are Nuclear transport, Positive regulation of chromosome organization, and Termination of RNA polymerase II transcription. Each is linked with MAP3K4 in more than 16 cancer types. Because this analysis shows association rather than direction, both MAP3K4-to-partner and partner-to-MAP3K4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Nuclear transport grouped by MAP3K4-low versus MAP3K4-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MAP3K4→partner) and Y-score (partner→MAP3K4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Nuclear transport →	+0.077	+0.887	<.001	<.001	3	17
BONE	Positive regulation of chromosome organization →	+0.074	+0.714	<.001	.001	3	16
LUNG_SCLC	Termination of RNA polymerase II transcription →	+0.146	+0.863	<.001	<.001	3	15
SOFT_TISSUE	Nucleocytoplasmic transport →	+0.076	+0.887	<.001	<.001	2	16
BONE	Nuclear export →	+0.110	+0.889	.001	<.001	3	14
OESOPHAGUS	Microtubule organizing center organization →	+0.094	+0.987	.002	.006	1	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,879 associations by consensus.

Nuclear transport by MAP3K4 expression — SOFT_TISSUE

Explore this box plot interactively →