MAP3K21

Across TCGA patient cohorts, MAP3K21 RNA expression is significantly associated with the protein abundance of many other proteins, with 21,518 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible MAP3K21-associated proteins across cancer lineages are POGK, PARP1, and RPRD2. Each is linked with MAP3K21 in more than 6 cancer types. Because this analysis shows association rather than direction, both MAP3K21-to-partner and partner-to-MAP3K21 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MAP3K21 versus POGK in HNSC, with a Pearson correlation of 0.44.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MAP3K21→partner) and Y-score (partner→MAP3K21) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	POGK →	+0.374	+0.937	<.001	<.001	3	7
HNSC	PARP1 →	+0.386	+0.814	<.001	<.001	3	6
LSCC	RPRD2 →	+0.314	+1.091	<.001	<.001	3	6
UCEC	UBE2Q1 →	+0.311	+0.887	<.001	.001	3	6
LUAD	ADAR →	+0.258	+0.709	<.001	<.001	3	6
LSCC	CDC73 →	+0.239	+0.918	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 21,518 associations by consensus.

MAP3K21 vs POGK — HNSC

Explore this scatter interactively →