MAP3K2-DT

Across TCGA patient cohorts, MAP3K2-DT RNA expression is significantly associated with the go_rna of many other GO terms, with 6,919 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible MAP3K2-DT-associated GO terms across cancer lineages are Mitochondrial gene expression, tRNA modification, and Mitochondrial respiratory chain complex assembly. Each is linked with MAP3K2-DT in more than 19 cancer types. Because this analysis shows association rather than direction, both MAP3K2-DT-to-partner and partner-to-MAP3K2-DT results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitochondrial gene expression grouped by MAP3K2-DT-low versus MAP3K2-DT-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MAP3K2-DT→partner) and Y-score (partner→MAP3K2-DT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Mitochondrial gene expression →	+0.034	+0.364	<.001	<.001	3	20
UVM	tRNA modification →	+0.039	+0.539	<.001	<.001	3	19
UVM	Mitochondrial respiratory chain complex assembly →	+0.052	+0.570	<.001	<.001	3	19
STAD	U2-type prespliceosome assembly →	+0.044	+0.355	<.001	<.001	3	18
UVM	Cytoplasmic translation →	+0.059	+0.512	<.001	<.001	3	18
ESCA	Intraciliary anterograde transport →	+0.069	+0.801	<.001	<.001	3	18

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,919 associations by consensus.

Mitochondrial gene expression by MAP3K2-DT expression — STAD

Explore this box plot interactively →