MAP3K14

Across TCGA patient cohorts, MAP3K14 protein abundance is significantly associated with the protein abundance of many other proteins, with 66 significant associations in total. GBM shows the largest number of these associations.

The most reproducible MAP3K14-associated proteins across cancer lineages are STOX2_S274, TIAL1_S278, and TMCC2_S75. Each is linked with MAP3K14 in more than 1 cancer types. Because this analysis shows association rather than direction, both MAP3K14-to-partner and partner-to-MAP3K14 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MAP3K14 versus STOX2_S274 in GBM, with a Pearson correlation of 0.50.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MAP3K14→partner) and Y-score (partner→MAP3K14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	STOX2_S274 →	+1.259	+0.923	.008	.002	2	1
GBM	TIAL1_S278 →	-0.800	-0.950	.002	.001	2	1
GBM	TMCC2_S75 →	+1.020	+1.030	.002	.004	2	1
GBM	XRCC4_S237 →	+0.673	+1.053	<.001	.005	2	1
GBM	CHMP5_S86 →	+1.363	+0.886	.003	.002	2	1
GBM	COL28A1_S758 →	-0.828	-0.879	<.001	.006	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 66 associations by consensus.

MAP3K14 vs STOX2_S274 — GBM

Explore this scatter interactively →