MAP3K14

Across TCGA cell cohorts, MAP3K14 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,176 significant associations in total. BONE shows the largest number of these associations.

The most reproducible MAP3K14-associated GO terms across cancer lineages are Protein depolymerization, Regulation of hippo signaling, and Non-canonical NF-kappaB signal transduction. Each is linked with MAP3K14 in more than 14 cancer types. Because this analysis shows association rather than direction, both MAP3K14-to-partner and partner-to-MAP3K14 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein depolymerization grouped by MAP3K14-low versus MAP3K14-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MAP3K14→partner) and Y-score (partner→MAP3K14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Protein depolymerization →	+0.132	+1.823	<.001	<.001	3	15
BONE	Regulation of hippo signaling →	+0.099	+1.557	<.001	.002	3	14
LUNG_SCLC	Non-canonical NF-kappaB signal transduction →	+0.089	+0.855	.002	.003	1	14
BONE	Negative regulation of cell killing →	+0.220	+2.098	<.001	<.001	3	12
STOMACH	Response to oscillatory fluid shear stress →	+0.203	+1.504	<.001	<.001	3	12
STOMACH	Cellular response to oscillatory fluid shear stress →	+0.203	+1.504	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,176 associations by consensus.

Protein depolymerization by MAP3K14 expression — BONE

Explore this box plot interactively →