MAP3K14-AS1

Across TCGA pan-cancer cohorts, MAP3K14-AS1 RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated MAP3K14-AS1 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher MAP3K14-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated MAP3K14-AS1 expression acts as an unfavorable survival marker, although some lineages such as BLCA and BRCA show a favorable association.

KIRC, UVM, and BLCA are the cancer types where MAP3K14-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Median	All	0.549	0.694	<.001	104	view →
UVM	DFS	Quartile	III,IV	0.282	1.000	.002	83	view →
BLCA	OS	Median	All	0.528	0.318	<.001	81	view →
CESC	DFS	Median	All	0.765	0.875	.001	48	view →
LGG	DFS	Median	All	0.685	0.788	.002	26	view →
BRCA	OS	Median	III,IV	0.884	0.772	.010	25	view →
ACC	DFS	Quartile	All	0.323	0.758	.002	25	view →
UCS	DFS	Tertile	IV	0.956	0.250	.024	24	view →
READ	OS	Median	II,III,IV	0.973	0.852	.005	21	view →
SKCM	OS	Quartile	All	0.445	0.207	<.001	20	view →
THCA	DFS	Tertile	IV	0.491	0.934	.003	15	view →
OV	DFS	Quartile	II,III,IV	0.321	0.419	.025	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

MAP3K14-AS1–KIRC (DFS)

Open the KIRC breakdown →