MAP3K14-AS1

Across TCGA pan-cancer cohorts, MAP3K14-AS1 RNA differs between tumor and matched normal tissue in 16 of 18 cancer types tested, making tumor–normal expression one of MAP3K14-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where MAP3K14-AS1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types MAP3K14-AS1 is over-expressed in tumor, although a few such as KICH show the opposite, repressed pattern.

BLCA, HNSC, and LUAD are the cancer types where MAP3K14-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MAP3K14-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BLCA	All	All	+0.891	<.001	9	view →
HNSC	All	III,IV	+0.549	<.001	9	view →
LUAD	Male	II,III,IV	+0.870	<.001	8	view →
KIRP	All	All	+0.374	.007	6	view →
KICH	All	All	−0.498	<.001	5	view →
UCEC	All	All	+0.468	.026	4	view →
STAD	All	All	+0.381	.001	4	view →
LUSC	All	All	+0.329	.001	3	view →
CHOL	All	All	+1.214	<.001	2	view →
PRAD	All	All	+0.349	.013	2	view →
COAD	Male	II,III,IV	+0.297	.048	2	view →
READ	Female	All	+0.588	.015	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 16 lineages.

MAP3K14-AS1–BLCA

Open the BLCA breakdown →