MAP3K13

Across TCGA cell cohorts, MAP3K13 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,815 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MAP3K13-associated GO terms across cancer lineages are Regulation of branching morphogenesis of a nerve, Regulation of neuron maturation, and Positive regulation of cell maturation. Each is linked with MAP3K13 in more than 13 cancer types. Because this analysis shows association rather than direction, both MAP3K13-to-partner and partner-to-MAP3K13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of branching morphogenesis of a nerve grouped by MAP3K13-low versus MAP3K13-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MAP3K13→partner) and Y-score (partner→MAP3K13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Regulation of branching morphogenesis of a nerve →	+0.378	+1.583	<.001	<.001	3	13
SOFT_TISSUE	Regulation of neuron maturation →	+0.786	+0.873	.001	.008	2	14
LIVER	Positive regulation of cell maturation →	+0.210	+0.720	.001	.002	3	13
LUNG_SCLC	Maintenance of centrosome location →	+0.145	+0.979	<.001	<.001	3	12
OVARY	Positive regulation of mitochondrial membrane potential →	+0.188	+1.088	<.001	<.001	3	10
OVARY	Regulation of cardiolipin metabolic process →	+0.135	+0.967	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,815 associations by consensus.

Regulation of branching morphogenesis of a nerve by MAP3K13 expression — OESOPHAGUS

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