MAP3K10

Across TCGA patient cohorts, MAP3K10 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,736 significant associations in total. GBM shows the largest number of these associations.

The most reproducible MAP3K10-associated proteins across cancer lineages are THOC5, GMPPA, and VPS13C. Each is linked with MAP3K10 in more than 4 cancer types. Because this analysis shows association rather than direction, both MAP3K10-to-partner and partner-to-MAP3K10 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MAP3K10 versus THOC5 in HNSC, with a Pearson correlation of 0.30.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MAP3K10→partner) and Y-score (partner→MAP3K10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	THOC5 →	+0.189	+0.421	.003	.008	3	4
GBM	GMPPA →	-0.268	-0.373	<.001	<.001	3	4
LSCC	VPS13C →	-0.210	-0.389	<.001	<.001	3	3
LSCC	XRCC1 →	+0.189	+0.396	.007	.002	3	3
GBM	TOR4A →	-0.325	-0.371	<.001	<.001	3	3
UCEC	TRAM1 →	-0.432	-0.541	<.001	.004	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,736 associations by consensus.

MAP3K10 vs THOC5 — HNSC

Explore this scatter interactively →