MAP2K6

Across TCGA cell cohorts, MAP2K6 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,897 significant associations in total. BONE shows the largest number of these associations.

The most reproducible MAP2K6-associated GO terms across cancer lineages are Detoxification of copper ion, Stress response to copper ion, and snRNA processing. Each is linked with MAP2K6 in more than 11 cancer types. Because this analysis shows association rather than direction, both MAP2K6-to-partner and partner-to-MAP2K6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Detoxification of copper ion grouped by MAP2K6-low versus MAP2K6-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MAP2K6→partner) and Y-score (partner→MAP2K6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Detoxification of copper ion →	-0.367	-1.530	<.001	<.001	3	12
BONE	Stress response to copper ion →	-0.367	-1.530	<.001	<.001	3	12
OVARY	snRNA processing →	+0.067	+1.205	<.001	.003	3	9
BONE	Dentinogenesis →	-1.848	-1.548	<.001	<.001	3	9
BONE	Regulation of double-strand break repair →	+0.077	+1.701	<.001	<.001	3	9
BONE	Positive regulation of double-strand break repair →	+0.073	+1.853	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,897 associations by consensus.

Detoxification of copper ion by MAP2K6 expression — BONE

Explore this box plot interactively →