MAP2K5

Across TCGA patient cohorts, MAP2K5 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,308 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible MAP2K5-associated proteins across cancer lineages are SIN3A, ANP32A, and MYEF2. Each is linked with MAP2K5 in more than 6 cancer types. Because this analysis shows association rather than direction, both MAP2K5-to-partner and partner-to-MAP2K5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MAP2K5 versus SIN3A in LSCC, with a Pearson correlation of 0.54.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MAP2K5→partner) and Y-score (partner→MAP2K5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	SIN3A →	+0.225	+0.412	<.001	<.001	3	6
OV	ANP32A →	+0.666	+0.422	<.001	.001	2	7
LSCC	MYEF2 →	+0.905	+0.527	<.001	<.001	3	5
HNSC	MYEF2_S17 →	+1.105	+0.408	<.001	.001	3	5
PDAC	TP53BP1_S1114 →	+0.377	+0.327	<.001	<.001	3	5
HNSC	FAM98B →	+0.304	+0.634	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,308 associations by consensus.

MAP2K5 vs SIN3A — LSCC

Explore this scatter interactively →