MAP1LC3B2

Across TCGA cell cohorts, MAP1LC3B2 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. STOMACH shows the largest number of these associations.

The most reproducible MAP1LC3B2-associated genes across cancer lineages are SCN10A, SPRR2B, and MS4A13. Each is linked with MAP1LC3B2 in more than 1 cancer types. Because this analysis shows association rather than direction, both MAP1LC3B2-to-partner and partner-to-MAP1LC3B2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SCN10A grouped by MAP1LC3B2-low versus MAP1LC3B2-high in STOMACH.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MAP1LC3B2→partner) and Y-score (partner→MAP1LC3B2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	SCN10A →	+0.006	+5.285	<.001	.003	3	1
STOMACH	SPRR2B →	+0.040	+5.285	<.001	.003	3	1
STOMACH	MS4A13 →	+0.133	+5.285	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

SCN10A by MAP1LC3B2 expression — STOMACH

Explore this box plot interactively →