MAP1LC3B

Across TCGA patient cohorts, MAP1LC3B mutation is significantly associated with the RNA expression of many other genes, with 28 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MAP1LC3B-associated genes across cancer lineages are RNA5SP412, MIR378E, and SNORA74C-1. Each is linked with MAP1LC3B in more than 1 cancer types. Because this analysis shows association rather than direction, both MAP1LC3B-to-partner and partner-to-MAP1LC3B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP412 grouped by MAP1LC3B-low versus MAP1LC3B-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MAP1LC3B→partner) and Y-score (partner→MAP1LC3B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP412 →	+1.012	+3.382	<.001	.004	3	1
UCEC	MIR378E →	+0.516	+4.132	<.001	.009	3	1
UCEC	SNORA74C-1 →	+0.431	+3.086	.002	.007	3	1
UCEC	FSBP →	+0.042	+4.315	.002	<.001	3	1
UCEC	LINC01173 →	+0.410	+3.169	<.001	.006	3	1
UCEC	RNU6-669P →	+0.424	+3.344	.002	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 28 associations by consensus.

RNA5SP412 by MAP1LC3B expression — UCEC

Explore this box plot interactively →