MAP1LC3A

Across TCGA patient cohorts, MAP1LC3A protein abundance is significantly associated with the RNA expression of many other genes, with 13,595 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible MAP1LC3A-associated genes across cancer lineages are MAP1B, PURG, and SRPX. Each is linked with MAP1LC3A in more than 8 cancer types. Because this analysis shows association rather than direction, both MAP1LC3A-to-partner and partner-to-MAP1LC3A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MAP1LC3A versus MAP1B in OV, with a Pearson correlation of 0.45.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MAP1LC3A→partner) and Y-score (partner→MAP1LC3A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	MAP1B →	+1.500	+0.569	<.001	<.001	3	9
HNSC	PURG →	+0.630	+0.842	.001	<.001	3	9
BRCA	SRPX →	+1.282	+0.662	<.001	<.001	3	8
OV	BACH2 →	+0.916	+0.672	<.001	<.001	3	8
HNSC	MYL3 →	+1.253	+0.663	.001	<.001	3	8
OV	DDR2 →	+1.228	+0.392	<.001	.003	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,595 associations by consensus.

MAP1LC3A vs MAP1B — OV

Explore this scatter interactively →