MAP1LC3A

Across TCGA patient cohorts, MAP1LC3A mutation is significantly associated with the immune_cell of many other genes, with 4 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MAP1LC3A-associated genes across cancer lineages are Endothelial cells, lymphatic Endothelial cells, and mv Endothelial cells. Each is linked with MAP1LC3A in more than 1 cancer types. Because this analysis shows association rather than direction, both MAP1LC3A-to-partner and partner-to-MAP1LC3A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Endothelial cells grouped by MAP1LC3A-low versus MAP1LC3A-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MAP1LC3A→partner) and Y-score (partner→MAP1LC3A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Endothelial cells →	-0.053	-2.957	.016	.037	1	1
UCEC	lymphatic Endothelial cells →	-0.030	-2.946	.031	.037	1	1
UCEC	mv Endothelial cells →	-0.034	-2.989	.014	.037	1	1
UCEC	NKT →	-0.132	-3.000	.032	.037	1	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

Endothelial cells by MAP1LC3A expression — UCEC

Explore this box plot interactively →