MAP1A

Across TCGA patient cohorts, MAP1A mutation is significantly associated with the RNA expression of many other genes, with 5,607 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MAP1A-associated genes across cancer lineages are ADAMTS15, AUNIP, and TIMM17A. Each is linked with MAP1A in more than 4 cancer types. Because this analysis shows association rather than direction, both MAP1A-to-partner and partner-to-MAP1A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ADAMTS15 grouped by MAP1A-low versus MAP1A-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MAP1A→partner) and Y-score (partner→MAP1A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ADAMTS15 →	-0.746	-1.611	.001	.002	3	5
UCEC	AUNIP →	+0.621	+1.392	<.001	<.001	3	5
COAD	TIMM17A →	+0.341	+2.665	.003	.004	3	5
COAD	CENPU →	+0.693	+2.727	<.001	.002	3	4
STAD	CHCHD4 →	+0.455	+3.484	.002	.002	3	4
UCEC	H2AZ1 →	+0.648	+1.970	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,607 associations by consensus.

ADAMTS15 by MAP1A expression — UCEC

Explore this box plot interactively →