MAP10

mass-spec protein & survival
Survivalmass-specKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, MAP10 mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated MAP10 data layer compared with 21 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher MAP10 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated MAP10 expression acts as an unfavorable survival marker, although some lineages such as CCRCC and PDAC show a favorable association.

CCRCC, PDAC, and LUAD are the cancer types where MAP10 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
CCRCCDFSMedianAll0.9510.657.0066view →
PDACOSTertileII,III,IV0.7570.294.0136view →
LUADDFSMedianAll0.7770.522.0333view →
Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

Exploration