MAP10

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, MAP10 mutation is significantly associated with the RNA expression of many other genes, with 5,574 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MAP10-associated genes across cancer lineages are RNA5SP248, RNA5SP411, and RNA5SP412. Each is linked with MAP10 in more than 2 cancer types. Because this analysis shows association rather than direction, both MAP10-to-partner and partner-to-MAP10 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MAP10→partner) and Y-score (partner→MAP10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUADRNA5SP248 →+0.482+4.293<.001.00833
UCECRNA5SP411 →+0.742+1.493<.001.00133
UCECRNA5SP412 →+0.486+1.597<.001.00133
UCECSNORD90 →+0.202+1.714<.001.00133
BRCAMIR6737 →+0.359+4.091<.001.00232
BLCALINC02706 →+0.096+6.217<.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 5,574 associations by consensus.

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