Across TCGA patient cohorts, MAP10 mutation is significantly associated with the total protein of many other genes, with 71 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MAP10-associated genes across cancer lineages are JNK_pT183_Y185, ASNS, and Caspase-7-cleavedD198. Each is linked with MAP10 in more than 2 cancer types. Because this analysis shows association rather than direction, both MAP10-to-partner and partner-to-MAP10 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MAP10→partner) and Y-score (partner→MAP10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	JNK_pT183_Y185 →	-0.158	-1.847	.001	.007	3	3
UCEC	ASNS →	+0.363	+1.530	<.001	.004	3	3
UCEC	Caspase-7-cleavedD198 →	+0.623	+2.341	<.001	<.001	3	3
COAD	C-Raf →	+0.175	+2.178	.011	.035	3	3
UCEC	14-3-3_beta →	-0.120	-2.780	<.001	<.001	3	2
UCEC	JNK2 →	+0.258	+2.331	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 71 associations by consensus.

Exploration

MAP10 survival (RNA) · tumor vs normal (RNA) · all MAP10 data types