MAP10

mutation — cross-omics
Cross-omicsMUTATION → DRUGCell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, MAP10 mutation is significantly associated with the drug of many other genes, with 39 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible MAP10-associated genes across cancer lineages are AT-7519, Omipalisib, and KIN001-260. Each is linked with MAP10 in more than 1 cancer types. Because this analysis shows association rather than direction, both MAP10-to-partner and partner-to-MAP10 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MAP10→partner) and Y-score (partner→MAP10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINEAT-7519 →+1.000+2.807.004.03232
LARGE_INTESTINEOmipalisib →+0.552+2.874.049.02132
LARGE_INTESTINEKIN001-260 →+0.419+2.807.019.04432
LARGE_INTESTINEPHA-793887 →+1.108+2.874<.001.02132
LARGE_INTESTINERU-SKI 43 →+0.451+2.807.006.04432
LARGE_INTESTINE5-Fluorouracil →+0.603+2.991.028.01831
Each partner links to its Q-omics profile. Showing the 6 strongest of 39 associations by consensus.

Exploration