MAOB

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, MAOB protein abundance is significantly associated with the RNA expression of many other genes, with 16,981 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible MAOB-associated genes across cancer lineages are ASPA, MGP, and ABCA8. Each is linked with MAOB in more than 7 cancer types. Because this analysis shows association rather than direction, both MAOB-to-partner and partner-to-MAOB results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MAOB versus ASPA in CCRCC, with a Pearson correlation of 0.45.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MAOB→partner) and Y-score (partner→MAOB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
CCRCCASPA →+1.418+0.521<.001<.00138
BRCAMGP →+1.533+0.622<.001<.00137
UCECABCA8 →+1.224+0.621<.001<.00137
LSCCFHL5 →+0.844+0.406<.001<.00136
OVC7 →+3.331+1.041<.001<.00136
BRCARAI2 →+1.659+0.869<.001<.00136
Each partner links to its Q-omics profile. Showing the 6 strongest of 16,981 associations by consensus.

MAOB vs ASPA — CCRCC

Per-sample scatter of MAOB vs ASPA in CCRCC (Pearson r = 0.45).

Explore this scatter interactively →

Exploration