MANSC1

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, MANSC1 protein abundance is significantly associated with the RNA expression of many other genes, with 5,086 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MANSC1-associated genes across cancer lineages are PDLIM7, ELAPOR1, and SH3BP4. Each is linked with MANSC1 in more than 2 cancer types. Because this analysis shows association rather than direction, both MANSC1-to-partner and partner-to-MANSC1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MANSC1 versus PDLIM7 in OV, with a Pearson correlation of -0.41.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MANSC1→partner) and Y-score (partner→MANSC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVPDLIM7 →-1.062-0.747<.001.00233
UCECELAPOR1 →+2.012+0.463<.001<.00133
BRCASH3BP4 →+0.669+0.342<.001.00133
UCECHAUS8 →-0.595-0.493.005.00333
UCECCXCL9 →-2.016-0.504.001.00633
UCECKIAA0319L →+0.536+0.603<.001<.00133
Each partner links to its Q-omics profile. Showing the 6 strongest of 5,086 associations by consensus.

MANSC1 vs PDLIM7 — OV

Per-sample scatter of MANSC1 vs PDLIM7 in OV (Pearson r = -0.41).

Explore this scatter interactively →

Exploration