Across TCGA patient cohorts, MANEALP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,704 significant associations in total. STAD shows the largest number of these associations.

The most reproducible MANEALP1-associated GO terms across cancer lineages are Macromolecule methylation, DNA-templated transcription elongation, and tRNA metabolic process. Each is linked with MANEALP1 in more than 21 cancer types. Because this analysis shows association rather than direction, both MANEALP1-to-partner and partner-to-MANEALP1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MANEALP1→partner) and Y-score (partner→MANEALP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Macromolecule methylation →	+0.067	+0.164	<.001	<.001	3	22
STAD	DNA-templated transcription elongation →	+0.059	+0.108	<.001	<.001	3	22
STAD	tRNA metabolic process →	+0.054	+0.105	<.001	<.001	3	22
ESCA	Telomere maintenance →	+0.063	+0.121	<.001	<.001	3	22
ESCA	Nuclear-transcribed mRNA catabolic process →	+0.063	+0.134	<.001	<.001	3	22
ESCA	Protein polyubiquitination →	+0.056	+0.105	<.001	.001	3	22

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,704 associations by consensus.

Exploration

MANEALP1 survival (RNA) · tumor vs normal (RNA) · all MANEALP1 data types