Across TCGA cell cohorts, MANEAL RNA expression is significantly associated with the RNA expression of many other genes, with 8,316 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible MANEAL-associated genes across cancer lineages are TIGD3, EPHA10, and CAMK2N2. Each is linked with MANEAL in more than 9 cancer types. Because this analysis shows association rather than direction, both MANEAL-to-partner and partner-to-MANEAL results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MANEAL→partner) and Y-score (partner→MANEAL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	TIGD3 →	+1.215	+1.920	<.001	<.001	3	10
LARGE_INTESTINE	EPHA10 →	+1.372	+1.682	<.001	<.001	3	8
LUNG_SCLC	CAMK2N2 →	+2.516	+2.374	<.001	<.001	3	8
LIVER	FBXO41 →	+1.481	+1.209	.001	.004	2	8
BREAST	PAFAH1B3 →	+1.007	+0.818	.003	.009	1	9
UPPER_AERODIGESTIVE_TRACT	TIMELESS →	+1.212	+1.736	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,316 associations by consensus.

Exploration

MANEAL survival (RNA) · tumor vs normal (RNA) · all MANEAL data types