MANEA

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, MANEA RNA expression is significantly associated with the protein abundance of many other proteins, with 10,483 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible MANEA-associated proteins across cancer lineages are UFL1, PARP1, and ZNF639_S200. Each is linked with MANEA in more than 4 cancer types. Because this analysis shows association rather than direction, both MANEA-to-partner and partner-to-MANEA results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MANEA versus UFL1 in GBM, with a Pearson correlation of 0.39.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MANEA→partner) and Y-score (partner→MANEA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMUFL1 →+0.327+0.489<.001<.00135
HNSCPARP1 →+0.528+0.805<.001<.00135
HNSCZNF639_S200 →+0.455+0.741<.001.00134
HNSCSCAF8 →+0.167+0.428<.001<.00134
HNSCCDC40 →+0.265+0.759<.001<.00134
HNSCCDK5RAP3 →+0.327+0.682<.001<.00134
Each partner links to its Q-omics profile. Showing the 6 strongest of 10,483 associations by consensus.

MANEA vs UFL1 — GBM

Per-sample scatter of MANEA vs UFL1 in GBM (Pearson r = 0.39).

Explore this scatter interactively →

Exploration