MANBA

Across TCGA cell cohorts, MANBA RNA expression is significantly associated with the go_rna of many other GO terms, with 4,685 significant associations in total. BONE shows the largest number of these associations.

The most reproducible MANBA-associated GO terms across cancer lineages are Glycosphingolipid catabolic process, Protein targeting to lysosome, and Glycoprotein catabolic process. Each is linked with MANBA in more than 10 cancer types. Because this analysis shows association rather than direction, both MANBA-to-partner and partner-to-MANBA results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Glycosphingolipid catabolic process grouped by MANBA-low versus MANBA-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MANBA→partner) and Y-score (partner→MANBA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Glycosphingolipid catabolic process →	+0.181	+1.321	<.001	<.001	3	11
STOMACH	Protein targeting to lysosome →	+0.087	+0.969	.005	.002	3	11
BONE	Glycoprotein catabolic process →	+0.183	+1.224	<.001	<.001	3	10
BONE	Positive regulation of protein exit from endoplasmic reticulum →	+0.174	+1.884	<.001	<.001	3	10
BONE	Ascending thin limb development →	+0.300	+1.524	<.001	.003	3	10
BONE	Metanephric ascending thin limb development →	+0.300	+1.524	<.001	.003	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,685 associations by consensus.

Glycosphingolipid catabolic process by MANBA expression — BONE

Explore this box plot interactively →