MAN2A1

Across TCGA cell cohorts, MAN2A1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,229 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MAN2A1-associated GO terms across cancer lineages are Mannose metabolic process, Viral gene expression, and Cellular response to environmental stimulus. Each is linked with MAN2A1 in more than 11 cancer types. Because this analysis shows association rather than direction, both MAN2A1-to-partner and partner-to-MAN2A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mannose metabolic process grouped by MAN2A1-low versus MAN2A1-high in LUNG_NSCLC_LUAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MAN2A1→partner) and Y-score (partner→MAN2A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	Mannose metabolic process →	+0.143	+1.133	<.001	<.001	3	12
SOFT_TISSUE	Viral gene expression →	+0.079	+1.325	<.001	<.001	3	11
LUNG_NSCLC_LUSC	Cellular response to environmental stimulus →	+0.055	+1.571	.002	.008	3	10
OESOPHAGUS	Viral protein processing →	+0.104	+0.765	.008	<.001	2	11
LUNG_NSCLC_LUSC	Cellular response to abiotic stimulus →	+0.055	+1.571	.002	.008	3	10
LUNG_NSCLC_LUSC	Regulation of protein exit from endoplasmic reticulum →	+0.103	+0.887	.001	.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,229 associations by consensus.

Mannose metabolic process by MAN2A1 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →