MAN1B1

Across TCGA patient cohorts, MAN1B1 protein abundance is significantly associated with the RNA expression of many other genes, with 12,461 significant associations in total. GBM shows the largest number of these associations.

The most reproducible MAN1B1-associated genes across cancer lineages are SURF4, PPP1R16B, and ZDHHC15. Each is linked with MAN1B1 in more than 5 cancer types. Because this analysis shows association rather than direction, both MAN1B1-to-partner and partner-to-MAN1B1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MAN1B1 versus SURF4 in OV, with a Pearson correlation of 0.42.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MAN1B1→partner) and Y-score (partner→MAN1B1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	SURF4 →	+0.505	+0.395	<.001	<.001	3	6
GBM	PPP1R16B →	-1.412	-0.244	<.001	<.001	3	5
CCRCC	ZDHHC15 →	-0.563	-0.330	<.001	<.001	3	4
GBM	CAB39L →	-0.828	-0.369	<.001	<.001	3	4
GBM	HLF →	-1.163	-0.393	<.001	<.001	3	4
PDAC	ART4 →	-0.983	-0.412	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,461 associations by consensus.

MAN1B1 vs SURF4 — OV

Explore this scatter interactively →