MAN1B1

Across TCGA cell cohorts, MAN1B1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,371 significant associations in total. CNS shows the largest number of these associations.

The most reproducible MAN1B1-associated GO terms across cancer lineages are Glycoprotein catabolic process, Regulation of macroautophagy, and Endoplasmic reticulum to cytosol transport. Each is linked with MAN1B1 in more than 14 cancer types. Because this analysis shows association rather than direction, both MAN1B1-to-partner and partner-to-MAN1B1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Glycoprotein catabolic process grouped by MAN1B1-low versus MAN1B1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MAN1B1→partner) and Y-score (partner→MAN1B1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Glycoprotein catabolic process →	+0.233	+1.240	<.001	<.001	3	15
STOMACH	Regulation of macroautophagy →	+0.094	+1.000	<.001	<.001	3	14
BONE	Endoplasmic reticulum to cytosol transport →	+0.146	+0.947	.001	.002	3	14
BONE	Proteoglycan catabolic process →	+0.269	+0.979	<.001	.001	3	14
BONE	Retrograde protein transport, ER to cytosol →	+0.146	+0.947	.001	.002	3	14
BONE	Viral life cycle →	+0.081	+0.913	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,371 associations by consensus.

Glycoprotein catabolic process by MAN1B1 expression — BONE

Explore this box plot interactively →