MAMSTR

Across TCGA cell cohorts, MAMSTR mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible MAMSTR-associated genes across cancer lineages are ASB17 and CDH9. Each is linked with MAMSTR in more than 1 cancer types. Because this analysis shows association rather than direction, both MAMSTR-to-partner and partner-to-MAMSTR results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ASB17 grouped by MAMSTR-low versus MAMSTR-high in OVARY.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MAMSTR→partner) and Y-score (partner→MAMSTR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	ASB17 →	+0.023	+5.807	<.001	.001	3	1
LARGE_INTESTINE	CDH9 →	+0.084	+3.793	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

ASB17 by MAMSTR expression — OVARY

Explore this box plot interactively →