MAMLD1

Across TCGA cell cohorts, MAMLD1 mutation is significantly associated with the RNA expression of many other genes, with 13 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible MAMLD1-associated genes across cancer lineages are F9, CYP4B1, and GLOD5. Each is linked with MAMLD1 in more than 1 cancer types. Because this analysis shows association rather than direction, both MAMLD1-to-partner and partner-to-MAMLD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, F9 grouped by MAMLD1-low versus MAMLD1-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MAMLD1→partner) and Y-score (partner→MAMLD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	F9 →	+0.015	+3.938	.007	.001	3	1
BLOOD_Lymphoma	CYP4B1 →	+0.301	+3.688	.004	.005	3	1
BLOOD_Lymphoma	GLOD5 →	+0.040	+3.321	.005	.006	3	1
BLOOD_Lymphoma	PTCHD3 →	+0.004	+3.584	<.001	.004	3	1
BLOOD_Lymphoma	CDSN →	+0.042	+3.807	<.001	.004	3	1
LUNG_NSCLC_LUAD	OR5H8 →	+0.017	+4.662	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 13 associations by consensus.

F9 by MAMLD1 expression — BLOOD_Lymphoma

Explore this box plot interactively →