Across TCGA patient cohorts, MAML3 protein abundance is significantly associated with the RNA expression of many other genes, with 1,848 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible MAML3-associated genes across cancer lineages are RN7SKP253, C1orf115, and CMYA5. Each is linked with MAML3 in more than 2 cancer types. Because this analysis shows association rather than direction, both MAML3-to-partner and partner-to-MAML3 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MAML3→partner) and Y-score (partner→MAML3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	RN7SKP253 →	+0.793	+0.613	<.001	<.001	3	3
UCEC	C1orf115 →	+0.799	+0.333	.003	.002	3	2
BRCA	CMYA5 →	+0.871	+0.391	<.001	.003	3	2
UCEC	DUXAP9 →	-1.283	-0.405	.002	.001	3	2
UCEC	EDRF1-AS1 →	+0.419	+0.274	.004	.001	3	2
COAD	SRPX2 →	-2.154	-2.117	.002	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,848 associations by consensus.

Exploration

MAML3 survival (RNA) · tumor vs normal (RNA) · all MAML3 data types