Across TCGA patient cohorts, MALRD1 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,468 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible MALRD1-associated proteins across cancer lineages are HSPB6, SMC2, and NARS1. Each is linked with MALRD1 in more than 3 cancer types. Because this analysis shows association rather than direction, both MALRD1-to-partner and partner-to-MALRD1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MALRD1→partner) and Y-score (partner→MALRD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	HSPB6 →	+0.766	+0.413	<.001	.008	3	4
LSCC	SMC2 →	-0.640	-0.745	<.001	<.001	3	4
OV	NARS1 →	-0.222	-0.081	.004	.006	3	4
BRCA	NCAPG →	-0.457	-0.682	<.001	.004	3	4
UCEC	CAVIN2 →	+0.848	+0.428	<.001	<.001	3	4
UCEC	KANK2 →	+0.604	+0.343	<.001	.002	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,468 associations by consensus.

Exploration

MALRD1 survival (RNA) · tumor vs normal (RNA) · all MALRD1 data types