MAL2

Across TCGA patient cohorts, MAL2 protein abundance is significantly associated with the RNA expression of many other genes, with 9,080 significant associations in total. GBM shows the largest number of these associations.

The most reproducible MAL2-associated genes across cancer lineages are SAMD12-AS1, MAL2-AS1, and SAMD12. Each is linked with MAL2 in more than 5 cancer types. Because this analysis shows association rather than direction, both MAL2-to-partner and partner-to-MAL2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MAL2 versus SAMD12-AS1 in OV, with a Pearson correlation of 0.40.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MAL2→partner) and Y-score (partner→MAL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	SAMD12-AS1 →	+0.530	+0.524	<.001	<.001	3	6
LSCC	MAL2-AS1 →	+0.883	+0.546	<.001	.001	3	6
GBM	SAMD12 →	+0.753	+0.682	<.001	<.001	3	4
GBM	TNFRSF14 →	-0.558	-0.615	<.001	<.001	3	4
COAD	SLAMF6 →	-0.958	-0.548	<.001	<.001	3	4
OV	NMU →	+1.098	+0.463	.002	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,080 associations by consensus.

MAL2 vs SAMD12-AS1 — OV

Explore this scatter interactively →