Across TCGA patient cohorts, MAK16 protein abundance is significantly associated with the protein abundance of many other proteins, with 22,683 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible MAK16-associated proteins across cancer lineages are SNRPD2, WDR74, and MPHOSPH10. Each is linked with MAK16 in more than 9 cancer types. Because this analysis shows association rather than direction, both MAK16-to-partner and partner-to-MAK16 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MAK16→partner) and Y-score (partner→MAK16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SNRPD2 →	+0.303	+0.381	<.001	<.001	3	10
LUAD	WDR74 →	+0.324	+0.411	<.001	<.001	3	10
LSCC	MPHOSPH10 →	+0.472	+0.451	<.001	<.001	3	10
OV	NPM1 →	+0.477	+0.423	<.001	<.001	3	10
BRCA	HNRNPK →	+0.257	+0.511	<.001	<.001	3	9
GBM	BMS1 →	+0.311	+0.348	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 22,683 associations by consensus.

Exploration

MAK16 survival (RNA) · tumor vs normal (RNA) · all MAK16 data types