MAK

Across TCGA patient cohorts, MAK protein abundance is significantly associated with the protein abundance of many other proteins, with 2,657 significant associations in total. GBM shows the largest number of these associations.

The most reproducible MAK-associated proteins across cancer lineages are TTF1, RBM5_S624, and RICTOR_S1235. Each is linked with MAK in more than 1 cancer types. Because this analysis shows association rather than direction, both MAK-to-partner and partner-to-MAK results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MAK versus TTF1 in OV, with a Pearson correlation of -0.72.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MAK→partner) and Y-score (partner→MAK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	TTF1 →	-0.719	-1.859	.003	<.001	3	2
OV	RBM5_S624 →	-0.876	-1.077	.003	.001	3	2
OV	RICTOR_S1235 →	-1.009	-1.549	<.001	<.001	3	2
OV	SND1_S426 →	+0.947	+1.342	.001	<.001	3	1
OV	SOX6_S411 →	+2.901	+1.387	<.001	<.001	3	1
OV	SP100_S180 →	-0.939	-1.315	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,657 associations by consensus.

MAK vs TTF1 — OV

Explore this scatter interactively →