MAGI1-AS1

Across TCGA pan-cancer cohorts, MAGI1-AS1 RNA differs between tumor and matched normal tissue in 6 of 18 cancer types tested, making tumor–normal expression one of MAGI1-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where MAGI1-AS1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types MAGI1-AS1 is over-expressed in tumor, although a few such as KIRC and BRCA show the opposite, repressed pattern.

KICH, KIRC, and STAD are the cancer types where MAGI1-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MAGI1-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KICH	All	All	+0.360	.001	5	view →
KIRC	All	II,III,IV	−0.037	.005	5	view →
STAD	All	All	+0.218	.012	2	view →
BRCA	All	III,IV	−0.153	.001	2	view →
CHOL	All	All	+0.115	.009	1	view →
LUAD	Female	II,III,IV	−0.060	.033	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 6 strongest of 6 lineages.

MAGI1-AS1–KICH

Open the KICH breakdown →