Across TCGA cell cohorts, MAGEE2 mutation is significantly associated with the RNA expression of many other genes, with 57 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MAGEE2-associated genes across cancer lineages are KCNG4, SLC5A8, and CST8. Each is linked with MAGEE2 in more than 1 cancer types. Because this analysis shows association rather than direction, both MAGEE2-to-partner and partner-to-MAGEE2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MAGEE2→partner) and Y-score (partner→MAGEE2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	KCNG4 →	+0.004	+4.415	<.001	.007	3	2
BLOOD_Leukemia	SLC5A8 →	+0.117	+4.786	<.001	<.001	3	2
LARGE_INTESTINE	CST8 →	+0.021	+4.415	<.001	.007	3	1
LARGE_INTESTINE	PZP →	+0.030	+4.467	<.001	.004	3	1
LARGE_INTESTINE	GPR6 →	+0.010	+5.022	<.001	.002	3	1
LARGE_INTESTINE	SPRR2G →	+0.605	+4.095	.008	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 57 associations by consensus.

Exploration

MAGEE2 survival (RNA) · tumor vs normal (RNA) · all MAGEE2 data types