Across TCGA cell cohorts, MAGED4B RNA expression is significantly associated with the go_rna of many other GO terms, with 4,253 significant associations in total. BONE shows the largest number of these associations.

The most reproducible MAGED4B-associated GO terms across cancer lineages are Negative regulation of syncytium formation by plasma membrane fusion, DNA-templated transcription initiation, and Regulation of termination of RNA polymerase II transcription. Each is linked with MAGED4B in more than 13 cancer types. Because this analysis shows association rather than direction, both MAGED4B-to-partner and partner-to-MAGED4B results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MAGED4B→partner) and Y-score (partner→MAGED4B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Negative regulation of syncytium formation by plasma membrane fusion →	+0.178	+3.266	<.001	<.001	3	14
BLOOD_Lymphoma	DNA-templated transcription initiation →	+0.074	+1.406	<.001	<.001	3	13
BONE	Regulation of termination of RNA polymerase II transcription →	+0.109	+1.695	<.001	.001	3	12
OESOPHAGUS	Cytoplasmic translation →	+0.143	+3.303	<.001	<.001	3	12
BONE	Regulation of termination of DNA-templated transcription →	+0.109	+1.695	<.001	.001	3	12
OESOPHAGUS	RNA splicing, via transesterification reactions →	+0.076	+2.603	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,253 associations by consensus.

Exploration

MAGED4B survival (RNA) · tumor vs normal (RNA) · all MAGED4B data types