MAGEB4

Across TCGA cell cohorts, MAGEB4 mutation is significantly associated with the mutation status of many other genes, with 1,863 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible MAGEB4-associated genes across cancer lineages are CNOT1, NHSL1, and GRM7. Each is linked with MAGEB4 in more than 2 cancer types. Because this analysis shows association rather than direction, both MAGEB4-to-partner and partner-to-MAGEB4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CNOT1 grouped by MAGEB4-low versus MAGEB4-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MAGEB4→partner) and Y-score (partner→MAGEB4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	CNOT1 →	+3.169	+4.548	.004	.004	1	3
SKIN	NHSL1 →	+3.392	+4.718	.002	.002	1	3
SKIN	GRM7 →	+3.169	+4.548	.004	.004	1	3
LARGE_INTESTINE	MYO7B →	+1.951	+3.015	.006	.006	1	3
LUNG_SCLC	EMILIN2 →	+5.066	+4.502	.007	.007	1	2
LUNG_SCLC	MEIS2 →	+5.066	+4.502	.007	.007	1	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,863 associations by consensus.

CNOT1 by MAGEB4 expression — SKIN

Explore this box plot interactively →