MAGEB18

Across TCGA patient cohorts, MAGEB18 mutation is significantly associated with the total protein of many other genes, with 49 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MAGEB18-associated genes across cancer lineages are Bcl-2, NF2, and Collagen-VI. Each is linked with MAGEB18 in more than 1 cancer types. Because this analysis shows association rather than direction, both MAGEB18-to-partner and partner-to-MAGEB18 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Bcl-2 grouped by MAGEB18-low versus MAGEB18-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MAGEB18→partner) and Y-score (partner→MAGEB18) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	Bcl-2 →	-0.423	-2.986	.026	.035	3	2
UCEC	NF2 →	+0.327	+2.321	<.001	.033	3	2
UCEC	Collagen-VI →	-0.252	-3.308	.005	.009	3	2
LUSC	GAPDH →	+0.917	+3.009	.008	.019	2	2
LUAD	Fibronectin →	+0.548	+3.321	.029	.010	3	1
LUAD	PDCD4 →	-0.443	-3.305	.034	.010	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 49 associations by consensus.

Bcl-2 by MAGEB18 expression — LUSC

Explore this box plot interactively →