MAGEB10

Across TCGA cell cohorts, MAGEB10 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible MAGEB10-associated genes across cancer lineages are OR2D3, SLC17A2, and APOC4. Each is linked with MAGEB10 in more than 1 cancer types. Because this analysis shows association rather than direction, both MAGEB10-to-partner and partner-to-MAGEB10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR2D3 grouped by MAGEB10-low versus MAGEB10-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MAGEB10→partner) and Y-score (partner→MAGEB10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	OR2D3 →	+0.035	+4.095	<.001	.009	3	1
LUNG_NSCLC_LUAD	SLC17A2 →	+0.012	+5.266	<.001	.001	3	1
LUNG_NSCLC_LUAD	APOC4 →	+0.050	+5.266	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

OR2D3 by MAGEB10 expression — LARGE_INTESTINE

Explore this box plot interactively →