Across TCGA patient cohorts, MAGEB1 mutation is significantly associated with the total protein of many other genes, with 44 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MAGEB1-associated genes across cancer lineages are Shc_pY317, ASNS, and 4E-BP1_pS65. Each is linked with MAGEB1 in more than 3 cancer types. Because this analysis shows association rather than direction, both MAGEB1-to-partner and partner-to-MAGEB1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MAGEB1→partner) and Y-score (partner→MAGEB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Shc_pY317 →	-0.166	-2.392	.001	<.001	3	3
LUSC	ASNS →	+0.909	+2.816	<.001	.036	1	4
LUAD	4E-BP1_pS65 →	+0.193	+3.012	.007	.018	3	2
UCEC	eEF2 →	+0.340	+3.169	.007	.018	3	2
LUSC	VHL →	+1.268	+2.816	.007	.036	3	2
UCEC	GAPDH →	+0.454	+2.700	.016	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 44 associations by consensus.

Exploration

MAGEB1 survival (RNA) · tumor vs normal (RNA) · all MAGEB1 data types