Across TCGA pan-cancer cohorts, MAGEB1 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of MAGEB1’s most consistent transcriptional readouts.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where MAGEB1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types MAGEB1 is over-expressed in tumor, although a few such as BRCA show the opposite, repressed pattern.

LIHC, UCEC, and BRCA are the cancer types where MAGEB1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MAGEB1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LIHC	All	All	+0.309	.005	3	view →
UCEC	All	IV	+0.245	.003	2	view →
BRCA	All	III,IV	−0.031	.026	2	view →
LUAD	All	All	+0.117	.033	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

Exploration

Same gene, other analysis: MAGEB1 RNA expression & survival · all MAGEB1 data types