MAGEA9B

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → DRUGCell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, MAGEA9B protein abundance is significantly associated with the drug of many other genes, with 13 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible MAGEA9B-associated genes across cancer lineages are Veliparib, TAK-715, and FR-180204. Each is linked with MAGEA9B in more than 1 cancer types. Because this analysis shows association rather than direction, both MAGEA9B-to-partner and partner-to-MAGEA9B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Veliparib grouped by MAGEA9B-low versus MAGEA9B-high in LUNG_SCLC.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MAGEA9B→partner) and Y-score (partner→MAGEA9B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUNG_SCLCVeliparib →+0.471+1.925.015.03431
LUNG_SCLCTAK-715 →+0.637+1.892.002.02231
LUNG_SCLCFR-180204 →-0.404-2.132.049.01831
LUNG_SCLCKIN001-260 →-0.564-2.132.011.01831
LUNG_SCLCBAY-MPS1 →+0.536+2.813.039.03321
LUNG_SCLCOSI-027 →-0.740-2.066.031.01421
Each partner links to its Q-omics profile. Showing the 6 strongest of 13 associations by consensus.

Veliparib by MAGEA9B expression — LUNG_SCLC

Box plot of Veliparib in MAGEA9B-low vs MAGEA9B-high samples in LUNG_SCLC.

Explore this box plot interactively →

Exploration