MAGEA9

Across TCGA patient cohorts, MAGEA9 mutation is significantly associated with the RNA expression of many other genes, with 21 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MAGEA9-associated genes across cancer lineages are RNA5SP411, LINC02563, and MIR4672. Each is linked with MAGEA9 in more than 1 cancer types. Because this analysis shows association rather than direction, both MAGEA9-to-partner and partner-to-MAGEA9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP411 grouped by MAGEA9-low versus MAGEA9-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MAGEA9→partner) and Y-score (partner→MAGEA9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP411 →	+2.283	+3.393	<.001	.007	3	1
UCEC	LINC02563 →	+0.214	+4.420	<.001	.001	3	1
UCEC	MIR4672 →	+0.938	+3.626	<.001	.004	3	1
UCEC	RNU4-56P →	+0.286	+4.582	.006	.005	3	1
UCEC	RNU6-1292P →	+0.426	+4.453	<.001	.006	3	1
UCEC	RNU6-1126P →	+0.429	+4.335	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 21 associations by consensus.

RNA5SP411 by MAGEA9 expression — UCEC

Explore this box plot interactively →